Slow-Cooker Pork Tenderloin

This tender slow-cooker pork tenderloin picks up tangy and sweet flavors from a tomato-based sauce that features the flavors of classic barbecue. Serve with crusty bread to sop up the sauce. Serve the leftover sauce with steamed hearty greens, creamy grits or shredded pork.

a recipe photo of the Slow Cooker Pork Tenderloin on a plate with sauce and a serving fork
Photo: Brie Goldman
Active Time:
15 mins
Total Time:
2 hrs 20 mins


  • 1 (15 ounce) can tomato puree

  • 1 (4 ounce) can chopped green chiles, undrained

  • 1 small sweet onion, finely chopped (about 1/2 cup)

  • 1 cup water

  • cup packed light brown sugar

  • cup cider vinegar

  • 2 tablespoons tomato paste

  • 1 tablespoon dry mustard

  • 1 teaspoon Worcestershire sauce

  • 1 teaspoon smoked paprika

  • ½ teaspoon garlic powder

  • ½ teaspoon onion powder

  • ½ teaspoon ground pepper

  • ¼ teaspoon salt

  • 1 (2 pound) pork tenderloin, trimmed


  1. Combine tomato puree, green chiles, onion, water, brown sugar, vinegar, tomato paste, mustard, Worcestershire, paprika, garlic powder, onion powder, pepper and salt in a 6-quart slow cooker; stir until combined.

  2. If needed, cut pork in half crosswise to fit inside the cooker. Add the pork to the sauce in the cooker; stir to coat. Cover and cook, flipping once, until a thermometer inserted into the thickest portion registers 145°F, 2 hours to 2 hours, 30 minutes on High or 3 to 4 hours on Low. Transfer the pork to a plate; cover with foil and let rest for 10 minutes.

  3. Meanwhile, use an immersion blender to puree the sauce in the slow cooker until smooth, about 1 minute. (Use caution when blending hot liquids.)

  4. Slice the pork into 1/2-inch-thick slices. Pour half of the sauce (about 2 cups) over the pork before serving. (Save any remaining sauce for another use.)

To make ahead

Refrigerate sauce in an airtight container for up to 4 days.


6-quart slow cooker

Nutrition Facts (per serving)

165 Calories
3g Fat
9g Carbs
25g Protein
Nutrition Facts
Servings Per Recipe 8
Serving Size 3 oz. pork & 1/4 cup sauce
Calories 165
% Daily Value *
Total Carbohydrate 9g 3%
Dietary Fiber 1g 4%
Total Sugars 7g
Added Sugars 4g 8%
Protein 25g 50%
Total Fat 3g 4%
Saturated Fat 1g 5%
Cholesterol 74mg 25%
Vitamin A 206IU 4%
Vitamin C 6mg 7%
Vitamin D 9IU 2%
Vitamin E 1mg 4%
Folate 5mcg 1%
Vitamin K 1mcg 1%
Sodium 177mg 8%
Calcium 20mg 2%
Iron 2mg 11%
Magnesium 39mg 9%
Potassium 621mg 13%
Zinc 2mg 18%
Vitamin B12 1mcg 42%

Nutrition information is calculated by a registered dietitian using an ingredient database but should be considered an estimate.

* Daily Values (DVs) are the recommended amounts of nutrients to consume each day. Percent Daily Value (%DV) found on nutrition labels tells you how much a serving of a particular food or recipe contributes to each of those total recommended amounts. Per the Food and Drug Administration (FDA), the daily value is based on a standard 2,000 calorie diet. Depending on your calorie needs or if you have a health condition, you may need more or less of particular nutrients. (For example, it’s recommended that people following a heart-healthy diet eat less sodium on a daily basis compared to those following a standard diet.)

(-) Information is not currently available for this nutrient. If you are following a special diet for medical reasons, be sure to consult with your primary care provider or a registered dietitian to better understand your personal nutrition needs.

Related Articles