Noodle-Less Butternut Squash Lasagna


Slices of butternut squash stand in for noodles in this veggie-packed lasagna with spinach, mushrooms and a creamy Parmesan cheese sauce. You can make the Parmesan cheese sauce with regular flour or swap in gluten-free flour to make this dish gluten-free. Look for a squash with a long, straight neck for the best results. Serve with a green salad for a vegetarian meal that you'd be happy to serve to company.

Prep Time:
50 mins
Additional Time:
1 hr 10 mins
Total Time:
2 hrs
8 cups


  • 3 cups low-fat milk, divided

  • ½ cup all-purpose flour or all-purpose gluten-free flour

  • 2 ounces reduced-fat cream cheese (3 tablespoons)

  • 1 cup grated Parmesan cheese

  • ½ teaspoon ground pepper, divided

  • ¼ teaspoon salt, divided

  • teaspoon ground nutmeg

  • 2 (10 ounce) packages frozen chopped spinach, thawed and squeezed dry

  • ½ cup part-skim ricotta

  • 2 tablespoons extra-virgin olive oil

  • 1 medium onion, chopped

  • 1 (8 ounce) package white mushrooms, sliced

  • 2 cloves garlic, minced

  • 1 teaspoon dried marjoram

  • ½ cup dry white wine

  • 2 pounds butternut squash, peeled and thinly sliced into rounds

  • ½ cup shredded Italian cheese blend


  1. Heat 2 1/2 cups milk in a large saucepan over medium heat until steaming. Meanwhile, whisk flour and the remaining 1/2 cup milk in a measuring cup until smooth; whisk into the hot milk. Whisk constantly until the sauce comes to a simmer and thickens. Continue cooking and stirring for 1 minute. Remove from heat and whisk in cream cheese, Parmesan, 1/4 teaspoon pepper, 1/8 teaspoon salt and nutmeg. Set aside.

  2. Combine spinach and ricotta in a medium bowl. Set aside.

  3. Heat oil in a large skillet over medium-high heat. Add onion and mushrooms; cook, stirring, until soft and browned, about 5 minutes. Add garlic, marjoram and the remaining 1/4 teaspoon pepper and 1/8 teaspoon salt; cook, stirring, for 1 minute. Add wine and simmer until the wine has nearly evaporated, 1 to 2 minutes. Remove from heat.

  4. Preheat oven to 400 degrees F. Lightly coat a 9-by-13-inch baking dish with cooking spray.

  5. Smear the bottom of the prepared dish with 1/2 cup of the cheese sauce. Line the bottom with a single layer of squash slices. Spread half the spinach mixture over the squash. Spoon on another 1/2 cup sauce. Add another layer of squash slices, then top with all of the mushroom mixture and another 1/2 cup sauce. Add a third layer of squash slices, the remaining spinach mixture and another 1/2 cup sauce. Finish with the remaining squash slices and sauce. Sprinkle with shredded cheese.

  6. Lightly coat a large piece of foil with cooking spray and tightly cover the dish. Bake for 45 minutes. Uncover and bake until bubbling and starting to brown, 15 to 20 minutes more. Let the lasagna stand for at least 10 minutes before serving.

    Noodle-Less Butternut Squash Lasagna

Nutrition Facts (per serving)

288 Calories
12g Fat
31g Carbs
15g Protein
Nutrition Facts
Servings Per Recipe 8
Serving Size 1 cup
Calories 288
% Daily Value *
Total Carbohydrate 31g 11%
Dietary Fiber 5g 17%
Total Sugars 9g
Protein 15g 31%
Total Fat 12g 15%
Saturated Fat 5g 26%
Cholesterol 27mg 9%
Vitamin A 18869IU 377%
Vitamin C 26mg 29%
Folate 168mcg 42%
Sodium 446mg 19%
Calcium 450mg 35%
Iron 3mg 16%
Magnesium 110mg 26%
Potassium 908mg 19%

Nutrition information is calculated by a registered dietitian using an ingredient database but should be considered an estimate.

* Daily Values (DVs) are the recommended amounts of nutrients to consume each day. Percent Daily Value (%DV) found on nutrition labels tells you how much a serving of a particular food or recipe contributes to each of those total recommended amounts. Per the Food and Drug Administration (FDA), the daily value is based on a standard 2,000 calorie diet. Depending on your calorie needs or if you have a health condition, you may need more or less of particular nutrients. (For example, it’s recommended that people following a heart-healthy diet eat less sodium on a daily basis compared to those following a standard diet.)

(-) Information is not currently available for this nutrient. If you are following a special diet for medical reasons, be sure to consult with your primary care provider or a registered dietitian to better understand your personal nutrition needs.

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