16 Dinner Casseroles to Help Reduce Inflammation

Chicken & Broccoli Casserole

Looking to reduce inflammation? Try one of these nutritious casserole dishes for dinner tonight. These dinner casseroles are packed with anti-inflammatory ingredients like broccoli, cauliflower, fish and whole grains to help alleviate inflammation. This includes keeping its pesky symptoms at bay, like mental fog, joint stiffness, high blood pressure and more. Recipes like our Chicken & Broccoli Casserole and Skillet Tuna Noodle Casserole are healthy, comforting and delicious options to help you feel your best.

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Chicken & Broccoli Casserole

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This one-pan chicken and broccoli casserole is prepared in a skillet on the stovetop, then finished in the oven until it's browned, cheesy and bubbling. Serve with a crunchy green salad.

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Cheesy Black Bean & Quinoa Skillet Casserole

Cheesy Black Bean & Quinoa Skillet Casserole
Rachel Marek

This Southwestern-inspired one-skillet casserole is stuffed with quinoa and plenty of fresh vegetables. Sharp Cheddar cheese flavors the filling and adds a layer of ooey-gooey melted cheese on top.

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Skillet Tuna Noodle Casserole

Skillet Tuna Noodle Casserole
Photography / Fred Hardy, Styling / Ruth Blackburn / Audrey Davis

Known as Tuna-Pea Wiggle to some, this family-friendly tuna noodle casserole tends to be made with canned soup and whole milk, which means high fat and sodium. We remedy this by making our own creamy mushroom sauce with nonfat milk thickened with a bit of flour. Look for whole-wheat egg noodles--they have more fiber than regular egg noodles (but this dish will work well and taste great with either).

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Vegetarian Enchilada Casserole

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Think of this vegetarian enchilada casserole as a veggie-packed Mexican-inspired lasagna with corn tortillas standing in for the noodles! If your peppers are mild and you like heat, opt for spicy pico de gallo. This easy vegetarian dinner recipe is sure to become a new family favorite.

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Salmon Noodle Casserole

a recipe photo of the Salmon Noodle Casserole
Photographer: Brie Goldman, Food Stylist: Charlie Worthington

This salmon noodle casserole is filled with creamy pasta, chunks of salmon and plenty of vegetables for a well-rounded meal. Dijon mustard flavors the dish, complementing the salmon and asparagus.

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Broccoli & Quinoa Casserole

Broccoli & Quinoa Casserole
Photography / Antonis Achilleos, Styling / Christine Keely, Ali Ramee

This broccoli-quinoa casserole makes a hearty vegetarian main dish. As the quinoa absorbs water and cooks, it creates the perfect amount of steam for cooking the broccoli. The broccoli is crisp-tender and adds texture to contrast with the creamy, cheesy quinoa. Swap in tricolor quinoa, if you prefer.

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Tuna Casserole with Peas

Tuna Casserole with Peas
Leslie Grow | Tuna Casserole with Peas

Maya Feller, M.S., RD, CDN, of Brooklyn-based Maya Feller Nutrition, has worked with many low-income families and is well-versed in the realities of putting food on the table that is healthy, affordable, tastes good, and isn't time-prohibitive. "A traditional tuna casserole provides both protein and carbohydrates to keep you full, and is kid-friendly and easy to make," she says about this tuna casserole recipe.

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Chicken & Cauliflower-Rice Casserole

Chicken & Cauliflower-Rice Casserole
Will Dickey

Get your veggies and your protein fix in this easy, gluten-free chicken and cauliflower-rice casserole. Riced cauliflower stands in for traditional rice, making this creamy casserole low in carbs but—with the simple combination of Cheddar cheese and chicken—suitable for even the pickiest of eaters.

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Cheesy Sweet Potato & Black Bean Casserole

Cheesy Sweet Potato & Black Bean Casserole
Ali Redmond

A cozy, cheesy casserole is classic comfort food. We amped up the nutrition by including plenty of nourishing veggies. Black beans provide powerful plant-based protein while the sweet potatoes offer up a healthy dose of vitamin A, an antioxidant important for vision and immunity.

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Stovetop Chicken & Broccoli Casserole

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We trimmed 9 grams of fat and almost 100 calories in this makeover of cheesy chicken-and-broccoli casserole. All the raw ingredients are layered in a skillet, then simmered for a quick weeknight dinner.

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Spinach & Tuna Noodle Casserole

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Homemade mushroom sauce kicks the can of soup out of the picture in this veggie-centric, healthy riff on a classic tuna-noodle casserole recipe. Serve with steamed green beans.

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Skillet Chicken Potpie

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A store-bought pie crust, frozen veggies and precooked chicken simplify the prep for this easy potpie. This healthy dinner recipe is comfort food at its best.

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Shrimp and Cauliflower Bake

Shrimp and Cauliflower Bake

This quick and easy seafood casserole gets bright flavor from fresh dill and feta cheese.

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Chicken, Quinoa & Sweet Potato Casserole

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This protein-loaded chicken and sweet potato casserole dish is made with multicolored quinoa, a blend of white, red and black varieties, but any color will work.

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Tuna Casserole with Orzo, Eggplant & Feta

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Tuna casserole is a timeless comfort-food recipe; this one incorporates eggplant, artichoke hearts, oregano, olives and feta cheese for a Greek-inspired flair.

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Salmon and Couscous Casserole

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Salmon is tossed with couscous, spinach, and roasted red peppers, then topped with toasted almonds for a light and easy meal that's ready in less than 30 minutes.

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