By Brierley Wright, M.S., R.D. , October 5, 2011 - 11:51am
Going gluten-free might not be as commonplace as going peanut-free—but you wouldn’t know it when you’re walking the grocery-store aisles. Gluten-free products are everywhere—and I’m sure that’s partly because these days ditching gluten appeals to more than just people with celiac disease.
But should you go gluten-free if you don’t have celiac disease? That was the topic of my column, “Ask our Nutritionist,”  in the current issue of EatingWell Magazine.
The short answer: not without checking in with your doctor first.
It’s important to test for celiac disease. (Have you tested positive? Find delicious gluten-free recipes, menus and health tips here.)  If you test negative, but you are experiencing gastrointestinal symptoms (bloating, cramping, diarrhea, constipation) after eating wheat, rye or barley, you could be “sensitive” to the gluten protein in them. (Find out which gluten-free grains and starches are “safe” here. )
The GI symptoms of “gluten sensitivity” (a.k.a. “gluten intolerance”) and celiac disease can be similar but, according to new, preliminary research published in the journal BMC Medicine, the immune system’s response is quite different.
With celiac disease, the immune system essentially targets the small intestine, flattening the tiny fingerlike projections, called villi, that line the gut and absorb nutrients from food, which can lead to malnutrition and weight loss.
Related: Are Stress and Stomach Upset Linked? Find out here. 
With gluten sensitivity, the immune system responds in a more urgent, nonspecific way—which is why people with gluten sensitivity have also reported having a “foggy mind,” depression, ADHD-like behavior, skin rash, anemia, joint pain and numbness in arms, fingers or legs. “Think of [the immune response of gluten sensitivity] as a SWAT team that responds immediately to any perceived threat and [that of celiac as] the investigative team that comes later with a long-term response,” says Alessio Fasano, M.D., study author and director of the University of Maryland Center for Celiac Research.
If you think you have a gluten sensitivity, speak with your doctor before eliminating gluten from your diet. A gluten-free diet is the only treatment recommended, but you should get tests for celiac and other forms of intestinal inflammation before changing your diet.
Have you eliminated gluten from your diet? Tell us what you think below.