A. Stevia has been touted as a "natural" sweetener and an alternative to sugar, but is it safe for us to consume? Though it seems this non-caloric sweetener just made its name recently, the stevia plant has a long history of use as a sweetener in South America. These newer stevia sweeteners—sold under brand names like Truvia, Stevia in the Raw or OnlySweet, and in blends with sugar, such as PureVia or Born Sweet Zing (at 8 to 10 calories per teaspoon)—include a highly purified extract of stevia called Rebaudioside A (a.k.a. Rebiana or Reb A). Reb A is 200 times sweeter than sugar and does not raise blood sugar.
Until December 2008, stevia and its derivatives could be sold in the U.S. only as dietary supplements, due to safety concerns. In the 1980s, animal studies linked stevia with adverse effects on fertility and reproductive development and possible genetic mutations. But in 2008, the makers of Truvia and PureVia submitted research to the Food and Drug Administration regarding Reb A's safety and petitioned for it to become a Generally Recognized as Safe (GRAS) ingredient.
The FDA affirmed, and still maintains, the GRAS status only for highly purified stevia extracts (Rebaudioside A, or Reb A). Whole stevia leafs, including products containing "crude stevia extract" or "whole leaf stevia," are not classified as GRAS because data is lacking on their effects on the cardiovascular, urinary and reproductive systems.
However, some consumer advocacy groups, like The Center for Science in the Public Interest (CSPI), criticize the quality of the studies (which are often done by the manufacturers themselves) and think the Reb A's GRAS status was granted prematurely. "In the past, FDA protocol required repeated testing in two separate animal species prior to approval, but in this case it didn't," says David Schardt, nutrition expert with CSPI. "We are not warning people to avoid Reb A, but the public should be aware that the FDA did not follow all the usual safeguards."
Despite being "natural," sugar substitutes like Stevia that earn the GRAS status usually don't have as much safety data as approved additives, meaning it's worth using Stevia sparingly—the daily acceptable dietary intake, or ADI, for Stevia is 9 packets.
Bottom Line: The FDA considers Reb A a safe sugar substitute, but has not approved other forms of stevia. If you want to use stevia, we suggest sticking with Reb A (look for it on the ingredient label), and using it sparingly.
I read just the opposite at Consumer Labs. They said the rebA extract was NOT safe and only the whole leaf was safe and how it is processed of course. Coke has a part in the extract "testing" and submitted it'w own since it had a green product in production and ready to come out. It had to have the FDA approval. It got it and the Coke product has come out. Comsumer labs says the best way to get pure Stevia Whole Leaf is to grown your own.
07/03/2014 - 3:58pm
I like the comment fro the 77 year old gentlemen !!! If the ''STEVIE'' work for him and is not called surgar by his Dr. more power to him. 'RIGHT ON' With all the comments made on it I will go by his.
Thank you Sir for posting youtrinfo.
06/30/2014 - 1:17am
The FDA approves things for one reason and one reason only. And that reason is money. Anyone who believes anything differently should wake up and smell the coffee (but first sweeten it with some Aspartame, we all need a good dose of neurotoxins to get us going in the morning).
06/27/2014 - 9:01am
Who would trust the FDA??? They refuse to do anything
about MSG - and it causes horrible side effects in a
whole lot of people . It's in almost everything !!!!
06/25/2014 - 12:42pm
James, this is why aspartame is DANGEROUS for our health!!! It is ALL for the MONEY!!!!!
Aspartame: By Far the Most Dangerous Substance Added to Most Foods Today
November 06, 2011
Aspartame is the technical name for the brand names NutraSweet, Equal, Spoonful, and Equal-Measure. It was discovered by accident in 1965 when James Schlatter, a chemist of G.D. Searle Company, was testing an anti-ulcer drug.
What you don't know WILL hurt you. Find out the dangerous effects of artificial sweeteners to your health. Aspartame was approved for dry goods in 1981 and for carbonated beverages in 1983. It was originally approved for dry goods on July 26, 1974, but objections filed by neuroscience researcher Dr. John W. Olney and consumer attorney James Turner in August 1974, as well as investigations of G.D. Searle's research practices caused the U.S. Food and Drug Administration (FDA) to put approval of aspartame on hold (December 5, 1974). In 1985, Monsanto purchased G.D. Searle and made Searle Pharmaceuticals and The NutraSweet Company separate subsidiaries.
Aspartame accounts for over 75 percent of the adverse reactions to food additives reported to the FDA. Many of these reactions are very serious, including seizures and death. A few of the 90 different documented symptoms listed in the report as part of aspartame dangers are:
Headaches/ migraines, Dizziness, Seizures, Nausea, Numbness,
Muscle spasms, Weight gain, Rashes, Depression, Fatigue,
Irritability, Tachycardia, Insomnia, Vision problems, Hearing loss,
Heart palpitations, Breathing difficulties, Anxiety attacks, Slurred speech, Loss of taste,
Tinnitus, Vertigo, Memory loss, Joint pain, and MANY MORE!!!
According to researchers and physicians studying the adverse effects of aspartame, the following chronic illnesses can be triggered or worsened by ingesting of aspartame:
Aspartame is made up of three chemicals: aspartic acid, phenylalanine, and methanol. The book Prescription for Nutritional Healing, by James and Phyllis Balch lists aspartame under the category of "chemical poison." As you shall see, that is exactly what it is.
What Is Aspartame Made Of?
Aspartic Acid (40 percent of Aspartame)
Dr. Russell L. Blaylock, a professor of neurosurgery at the Medical University of Mississippi, recently published a book thoroughly detailing the damage that is caused by the ingestion of excessive aspartic acid from aspartame. Blaylock makes use of almost 500 scientific references to show how excess free excitatory amino acids such as aspartic acid and glutamic acid (about 99 percent of monosodium glutamate or MSG is glutamic acid) in our food supply are causing serious chronic neurological disorders and a myriad of other acute symptoms.
How Aspartate (and Glutamate) Cause Damage
Aspartate and glutamate act as neurotransmitters in the brain by facilitating the transmission of information from neuron to neuron. Too much aspartate or glutamate in the brain kills certain neurons by allowing the influx of too much calcium into the cells. This influx triggers excessive amounts of free radicals, which kill the cells. The neural cell damage that can be caused by excessive aspartate and glutamate is why they are referred to as "excitotoxins." They "excite" or stimulate the neural cells to death.
Aspartic acid is an amino acid. Taken in its free form (unbound to proteins), it significantly raises the blood plasma level of aspartate and glutamate. The excess aspartate and glutamate in the blood plasma shortly after ingesting aspartame or products with free glutamic acid (glutamate precursor) leads to a high level of those neurotransmitters in certain areas of the brain.
The blood brain barrier (BBB), which normally protects the brain from excess glutamate and aspartate as well as toxins, 1) is not fully developed during childhood, 2) does not fully protect all areas of the brain, 3) is damaged by numerous chronic and acute conditions, and 4) allows seepage of excess glutamate and aspartate into the brain even when intact.
The excess glutamate and aspartate slowly begin to destroy neurons. The large majority (75 percent or more) of neural cells in a particular area of the brain are killed before any clinical symptoms of a chronic illness are noticed. A few of the many chronic illnesses that have been shown to be contributed to by long-term exposure to excitatory amino acid damage include:
Multiple sclerosis (MS) Parkinson's disease
ALS Hypoglycemia Memory loss AIDS Hormonal problems Dementia
Epilepsy Brain lesions Alzheimer's disease Neuroendocrine disorders
The risk to infants, children, pregnant women, the elderly and persons with certain chronic health problems from excitotoxins are great. Even the Federation of American Societies for Experimental Biology (FASEB), which usually understates problems and mimics the FDA party-line, recently stated in a review that glutamic acid should be avoided by women of childbearing age.
Aspartic acid from aspartame has the same deleterious effects on the body as glutamic acid isolated from it's naturally protein-bound state, causing it to become a neurotoxin instead of a non-essential amino acid.
Aspartame in diet sodas, or aspartame in other liquid form are absorbed more quickly and have been shown to spike plasma levels of aspartic acid.
The exact mechanism of acute reactions to excess free glutamate and aspartate is currently being debated. As reported to the FDA, those reactions include:
One common complaint of persons suffering from the effect of aspartame is memory loss. Ironically, in 1987, G.D. Searle, the manufacturer of aspartame, undertook a search for a drug to combat memory loss caused by excitatory amino acid damage. Blaylock is one of many scientists and physicians who are concerned about excitatory amino acid damage caused by ingestion of aspartame and MSG.
A few of the many experts who have spoken out against the damage being caused by aspartate and glutamate include Adrienne Samuels, Ph.D., an experimental psychologist specializing in research design. Another is Olney, a professor in the department of psychiatry, School of Medicine, Washington University, a neuroscientist and researcher, and one of the world's foremost authorities on excitotoxins. (He informed Searle in 1971 that aspartic acid caused holes in the brains of mice.)
Phenylalanine (50 percent of aspartame)
Don't let artificial sweeteners fool you! Find out the risks of using aspartame. Phenylalanine is an amino acid normally found in the brain. Persons with the genetic disorder phenylketonuria (PKU) cannot metabolize phenylalanine. This leads to dangerously high levels of phenylalanine in the brain (sometimes lethal). It has been shown that ingesting aspartame, especially along with carbohydrates, can lead to excess levels of phenylalanine in the brain even in persons who do not have PKU.
This is not just a theory, as many people who have eaten large amounts of aspartame over a long period of time and do not have PKU have been shown to have excessive levels of phenylalanine in the blood. Excessive levels of phenylalanine in the brain can cause the levels of serotonin in the brain to decrease, leading to emotional disorders such as depression. It was shown in human testing that phenylalanine levels of the blood were increased significantly in human subjects who chronically used aspartame.
Even a single use of aspartame raised the blood phenylalanine levels. In his testimony before the U.S. Congress, Dr. Louis J. Elsas showed that high blood phenylalanine can be concentrated in parts of the brain and is especially dangerous for infants and fetuses. He also showed that phenylalanine is metabolized much more efficiently by rodents than by humans.
One account of a case of extremely high phenylalanine levels caused by aspartame was recently published by the Wednesday Journal in an article titled "An Aspartame Nightmare." John Cook began drinking six to eight diet drinks every day. His symptoms started out as memory loss and frequent headaches. He began to crave more aspartame-sweetened drinks. His condition deteriorated so much that he experienced wide mood swings and violent rages. Even though he did not suffer from PKU, a blood test revealed a phenylalanine level of 80 mg/dl. He also showed abnormal brain function and brain damage. After he kicked his aspartame habit, his symptoms improved dramatically.
As Blaylock points out in his book, early studies measuring phenylalanine buildup in the brain were flawed. Investigators who measured specific brain regions and not the average throughout the brain notice significant rises in phenylalanine levels. Specifically the hypothalamus, medulla oblongata, and corpus striatum areas of the brain had the largest increases in phenylalanine. Blaylock goes on to point out that excessive buildup of phenylalanine in the brain can cause schizophrenia or make one more susceptible to seizures.
Therefore, long-term, excessive use of aspartame may provide a boost to sales of serotonin reuptake inhibitors such as Prozac and drugs to control schizophrenia and seizures.
Methanol a.k.a wood alcohol/poison (10 percent of aspartame)
Methanol/wood alcohol is a deadly poison. Some people may remember methanol as the poison that has caused some "skid row" alcoholics to end up blind or dead. Methanol is gradually released in the small intestine when the methyl group of aspartame encounters the enzyme chymotrypsin.
The absorption of methanol into the body is sped up considerably when free methanol is ingested. Free methanol is created from aspartame when it is heated to above 86 Fahrenheit (30 Centigrade). This would occur when aspartame-containing product is improperly stored or when it is heated (e.g. as part of a "food" product such as Jello).
Methanol breaks down into formaldehyde in the body. Formaldehyde is a deadly neurotoxin. An EPA assessment of methanol states that methanol "is considered a cumulative poison due to the low rate of excretion once it is absorbed. In the body, methanol is oxidized to formaldehyde." They recommend a limit of consumption of 7.8 mg/day. A one-liter (approx. 1 quart) aspartame-sweetened beverage contains about 56 mg of methanol. Heavy users of aspartame-containing products consume as much as 250 mg of methanol daily or 32 times the EPA limit.
Symptoms from methanol poisoning include headaches, ear buzzing, dizziness, nausea, gastrointestinal disturbances, weakness, vertigo, chills, memory lapses, numbness and shooting pains in the extremities, behavioral disturbances, and neuritis. The most well known problems from methanol poisoning are vision problems including misty vision, progressive contraction of visual fields, blurring of vision, obscuration of vision, retinal damage, and blindness. Formaldehyde is a known carcinogen, causes retinal damage, interferes with DNA replication and causes birth defects.
Due to the lack of a couple of key enzymes, humans are many times more sensitive to the toxic effects of methanol than animals. Therefore, tests of aspartame or methanol on animals do not accurately reflect the danger for humans. As pointed out by Dr. Woodrow C. Monte, director of the food science and nutrition laboratory at Arizona State University: "There are no human or mammalian studies to evaluate the possible mutagenic, teratogenic or carcinogenic effects of chronic administration of methyl alcohol."
He was so concerned about the unresolved safety issues that he filed suit with the FDA requesting a hearing to address these issues. He asked the FDA to:
"...[S]low down on this soft drink issue long enough to answer some of the important questions. It's not fair that you are leaving the full burden of proof on the few of us who are concerned and have such limited resources. You must remember that you are the American public's last defense. Once you allow usage (of aspartame) there is literally nothing I or my colleagues can do to reverse the course. Aspartame will then join saccharin, the sulfiting agents, and God knows how many other questionable compounds enjoined to insult the human constitution with governmental approval."
Shortly thereafter, the Commissioner of the FDA, Arthur Hull Hayes, Jr., approved the use of aspartame in carbonated beverage. He then left for a position with G.D. Searle's public relations firm.
It has been pointed out that some fruit juices and alcoholic beverages contain small amounts of methanol. It is important to remember, however, that methanol never appears alone. In every case, ethanol is present, usually in much higher amounts. Ethanol is an antidote for methanol toxicity in humans. The troops of Desert Storm were "treated" to large amounts of aspartame-sweetened beverages, which had been heated to over 86 degrees F in the Saudi Arabian sun. Many of them returned home with numerous disorders similar to what has been seen in persons who have been chemically poisoned by formaldehyde. The free methanol in the beverages may have been a contributing factor in these illnesses. Other breakdown products of aspartame such as DKP (discussed below) may also have been a factor.
In a 1993 act that can only be described as "unconscionable," the FDA approved aspartame as an ingredient in numerous food items that would always be heated to above 86 degree F (30 degree C).
DKP is a byproduct of aspartame metabolism. DKP has been implicated in the occurrence of brain tumors. Olney noticed that DKP, when nitrosated in the gut, produced a compound that was similar to N-nitrosourea, a powerful brain tumor causing chemical. Some authors have said that DKP is produced after aspartame ingestion. I am not sure if that is correct. It is definitely true that DKP is formed in liquid aspartame-containing products during prolonged storage.
G.D. Searle conducted animal experiments on the safety of DKP. The FDA found numerous experimental errors occurred, including "clerical errors, mixed-up animals, animals not getting drugs they were supposed to get, pathological specimens lost because of improper handling," and many other errors. These sloppy laboratory procedures may explain why both the test and control animals had 16 times more brain tumors than would be expected in experiments of this length.
In an ironic twist, shortly after these experimental errors were discovered, the FDA used guidelines recommended by G.D. Searle to develop the industry-wide FDA standards for good laboratory practices.
DKP has also been implicated as a cause of uterine polyps and changes in blood cholesterol by FDA Toxicologist Dr. Jacqueline Verrett in her testimony before the U.S. Senate.
06/14/2014 - 8:01am
This Reb-A con concoction you speak of isn't stevia at all. Its like saying beer is wheat because beer comes from wheat. Stevia is a plant people, Reb-A is a chemical those two things are very different.
06/06/2014 - 1:29am
Shirl, please spell it correctly. It is Stevia with an A on the end. Not Stevie. Stevie is a person's name, like Stevie Wonder or Stevie Nicks. Thanks.
06/05/2014 - 12:23pm
I kept having dizzy nauseous spells that would come on suddenly. After looking back and tracing what I had eaten the common denominator was Stevia. It was not something I ate often but each time I had the same reaction and feeling that hit suddenly. Just a FYI. I stay away from stevia now and have not had the dizziness. It does lower blood pressure so makes sense.
05/25/2014 - 12:47am
I'm 77 and I use PURE STEVIE and not anything else that SAYS it is Stevie, this and that. My Dr. told me that my body does not recolonize Stevie as sugar, because it is not! I have Diabetes and I control it with exercise, diet and Stevie, IT is type 2. PEOPLE, WE NEED TO EDUCATE OURSELVES!!!!!!!!!!!!!!!!!!!!!
about our own health. I personally will continue to use it and learn more about it, canning, cooking, baking,
and anything else I can. That is how I feel and I am not telling anyone else to use anything that they don't know about. LEARN LEARN AND THEN LEARN SOME MORE, It is never to late.!!!!!!!
05/23/2014 - 11:21am
Who reasons eating something based on the FDA? They've approved terrible things and banned great. Happens all the time; it's a business.