Dietary cholesterol comes only from animal foods. Potato chips, along with fruits, vegetables and whole grains, have no cholesterol. However, be sure to check the nutrition facts label on the potato chip bag for saturated fat, which causes your body to produce more cholesterol. Potato chips are also high in calories. Lastly, check the serving size and do the math: if you eat 2 servings' worth, you've taken in double the calories and saturated fat.